Notable upsets in the Quarterfinals of the U.S. Open Cup
There have only been six "upsets" in the quarterfinal round of the U.S. Open Cup since 1995, therefore all four of them are, in fact, "notable." You could argue there has been seven, but we didn’t think the Seattle Sounders (USL-1) eliminating the Kansas City Wizards (MLS) on penalty kicks was much of an upset in 2008.
Tampa Bay Mutiny (MLS) 3 : 4 (asdet) Rochester Raging Rhinos (A-League)
September 7, 1996
Frontier Field - Rochester, NY
In front of more than 12,000 fans at Frontier Field, the Rochester Raging Rhinos knocked off Major League Soccer’s best team, the Tampa Bay Mutiny, in sudden death overtime.